ncRNA name | hsa-let-7b |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples, normal retinas |
Methods | microarray, qRT-PCR |
Expression pattern | down-regulated |
Functional description | let-7b was on average B50-fold lower in abundance in retinoblastoma versus healthy retina. This downregulation is widespread across retinoblastoma; 9/10 of these samples from different individuals had lower let-7b levels than the average let-7b expression in five retina samples from healthy individuals. |
PubMed ID | 18026111 |
Year | 2007 |
Title | Using expression profiling data to identify human microRNA targets. |
Drug-related ncRNA | NO |
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